Projects Funded by ECOFECT

Projects Funded by ECOFECT

LEGCOXINET Project

Title : Exploring the functional, ecological and evolutionary relationships between Legionella and Coxiella T4SS effectors and the host autophagy machinery.
Co-holders: Patricia Doublet - "Legionella Pathogenesis" team and Fabrice Vavre - "Genetics and Evolution of Host-Parasite Interactions" team
Other ECOFECT partners: Guy Perrière - "Bioinformatics and Evolutionary Genomics" team, Mathias Faure - "Autophagy, Infection, Immunity" team, Lionel Zenner - "Genetics and Evolution of Host-Parasite Interactions" team, Elsa Jourdain - "Animal Epidemiology" team.
Duration of the project: 3 years
Funding: one PhD grant and benchfees
PhD student: Virginie Lelogeais

VMMTSS Project

Title : Impact of vaginal microbiote on the development of menstrual toxic shock syndrome.
Co-holders : Gérard Lina - team "Staphylococcal Pathogenesis" and Claire Prigent-Combaret - team "Rhizosphere"
Other ECOFECT partners: Jean Thioulouse (team: "Bioinformatics and Evolutionary Genomics")
Duration of the project: 3 years
Funding: one PhD grant and benchfees
PhD student: Isaline Jacquemond

DENGEVOLOMICS Project

Title: Functional study of genetics interactions between Dengue virus and its mosquito vector by experimental evolution.
Co-holders: Marlène Dreux - "Enveloped Viruses, Vectors and Innate Responses" team and Bastien Boussau – "Bioinformatics and Evolutionary Genomics" team
Other partners: Mathilde Paris, Institut de biologie du développement / "Evolution et développement de la morphologie et des comportements"
Duration of the project: 3 years
Funding: one post-doctoral grant and benchfees

INTRACELL-X-EVO Project

Title: Experimental evolution of an intracellular bacterium within its host cell
Co-holders: Thomas Henry - "Inflammasome and Bacterial Infections" team, Eric Tannier - "Bioinformatics and Evolutionary Genomics" team
Other partner: Dominique Schneider, laboratory "Adaptation et pathogénie des Microorganismes"
Duration of the project: 3 years
Funding: one post-doctorate grant and benchfees

EVO-FIT-COMBO-TB.

Title: Microevolution and fitness modulation of Mycobacterium tuberculosis exposed to two-drug combinations: in vitro experiment and mathematical modeling
Co-holders: Oana Dumitrescu - "Staphylococcal Pathogenesis" team and Sylvain Goutelle - "Evaluation and Modeling of Therapeutic Effects" team
Other partners: Jean-Pierre Flandrois - "Bioinformatics and Evolutionary Genomics" ECOFECT team and Catherine Legras-Lachuer, ProfileXpert, Microgenomics and Genomics service
Duration of the project: 2 years
Funding: one post-doctoral grant and benchfees